Predictive factors for pneumonia development and progression to respiratory failure in MERS-CoV infected patients
Identifieur interne : 001065 ( Main/Exploration ); précédent : 001064; suivant : 001066Predictive factors for pneumonia development and progression to respiratory failure in MERS-CoV infected patients
Auteurs : Jae-Hoon Ko [Corée du Sud] ; Ga Eun Park [Corée du Sud] ; Ji Yeon Lee [Corée du Sud] ; Ji Yong Lee [Corée du Sud] ; Sun Young Cho [Corée du Sud] ; Young Eun Ha [Corée du Sud] ; Cheol-In Kang [Corée du Sud] ; Ji-Man Kang [Corée du Sud] ; Yae-Jean Kim [Corée du Sud] ; Hee Jae Huh [Corée du Sud] ; Chang-Seok Ki [Corée du Sud] ; Byeong-Ho Jeong [Corée du Sud] ; Jinkyeong Park [Corée du Sud] ; Chi Ryang Chung [Corée du Sud] ; Doo Ryeon Chung [Corée du Sud] ; Jae-Hoon Song [Corée du Sud] ; Kyong Ran Peck [Corée du Sud]Source :
- The Journal of Infection [ 0163-4453 ] ; 2016.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Comorbidité, Dossiers médicaux électroniques, Facteurs de risque, Femelle, Flambées de maladies, Humains, Hôpitaux universitaires, Infections à coronavirus (physiopathologie), Infections à coronavirus (épidémiologie), Insuffisance respiratoire (épidémiologie), Mâle, Pneumopathie infectieuse (physiopathologie), Pneumopathie infectieuse (épidémiologie), République de Corée (épidémiologie), Sujet âgé, Évolution de la maladie.
- MESH :
- physiopathologie : Infections à coronavirus, Pneumopathie infectieuse.
- épidémiologie : Infections à coronavirus, Insuffisance respiratoire, Pneumopathie infectieuse, République de Corée.
- Adulte, Adulte d'âge moyen, Comorbidité, Dossiers médicaux électroniques, Facteurs de risque, Femelle, Flambées de maladies, Humains, Hôpitaux universitaires, Mâle, Sujet âgé, Évolution de la maladie.
English descriptors
- KwdEn :
- Adult, Aged, Comorbidity, Coronavirus Infections (epidemiology), Coronavirus Infections (physiopathology), Disease Outbreaks, Disease Progression, Electronic Health Records, Female, Hospitals, University, Humans, Male, Middle Aged, Pneumonia (epidemiology), Pneumonia (physiopathology), Republic of Korea (epidemiology), Respiratory Insufficiency (epidemiology), Risk Factors.
- MESH :
- epidemiology : Coronavirus Infections, Pneumonia, Republic of Korea, Respiratory Insufficiency.
- physiopathology : Coronavirus Infections, Pneumonia.
- Adult, Aged, Comorbidity, Disease Outbreaks, Disease Progression, Electronic Health Records, Female, Hospitals, University, Humans, Male, Middle Aged, Risk Factors.
Abstract
After the 2015 Middle East respiratory syndrome (MERS) outbreak in Korea, prediction of pneumonia development and progression to respiratory failure was emphasized in control of MERS outbreak.
MERS-CoV infected patients who were managed in a tertiary care center during the 2015 Korean MERS outbreak were reviewed. To analyze predictive factors for pneumonia development and progression to respiratory failure, we evaluated clinical variables measured within three days from symptom onset.
A total of 45 patients were included in the study: 13 patients (28.9%) did not develop pneumonia, 19 developed pneumonia without respiratory failure (42.2%), and 13 progressed to respiratory failures (28.9%). The identified predictive factors for pneumonia development included age ≥45 years, fever ≥37.5 °C, thrombocytopenia, lymphopenia, CRP ≥ 2 mg/dL, and a threshold cycle value of PCR less than 28.5. For respiratory failure, the indicators included male, hypertension, low albumin concentration, thrombocytopenia, lymphopenia, and CRP ≥ 4 mg/dL (all
For successful control of MERS outbreak, MERS-CoV infected patients with ≥ two predictive factors should be intensively managed from the initial presentation.
Url:
DOI: 10.1016/j.jinf.2016.08.005
PubMed: 27519621
PubMed Central: 7112644
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000E65
- to stream Pmc, to step Curation: 000E65
- to stream Pmc, to step Checkpoint: 000A36
- to stream PubMed, to step Corpus: 001005
- to stream PubMed, to step Curation: 001005
- to stream PubMed, to step Checkpoint: 000F40
- to stream Ncbi, to step Merge: 001743
- to stream Ncbi, to step Curation: 001743
- to stream Ncbi, to step Checkpoint: 001743
- to stream Main, to step Merge: 001069
- to stream Main, to step Curation: 001065
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Predictive factors for pneumonia development and progression to respiratory failure in MERS-CoV infected patients</title><author><name sortKey="Ko, Jae Hoon" sort="Ko, Jae Hoon" uniqKey="Ko J" first="Jae-Hoon" last="Ko">Jae-Hoon Ko</name><affiliation wicri:level="1"><nlm:aff id="aff1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Park, Ga Eun" sort="Park, Ga Eun" uniqKey="Park G" first="Ga Eun" last="Park">Ga Eun Park</name><affiliation wicri:level="1"><nlm:aff id="aff1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Lee, Ji Yeon" sort="Lee, Ji Yeon" uniqKey="Lee J" first="Ji Yeon" last="Lee">Ji Yeon Lee</name><affiliation wicri:level="1"><nlm:aff id="aff1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Lee, Ji Yong" sort="Lee, Ji Yong" uniqKey="Lee J" first="Ji Yong" last="Lee">Ji Yong Lee</name><affiliation wicri:level="1"><nlm:aff id="aff1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Cho, Sun Young" sort="Cho, Sun Young" uniqKey="Cho S" first="Sun Young" last="Cho">Sun Young Cho</name><affiliation wicri:level="1"><nlm:aff id="aff1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Ha, Young Eun" sort="Ha, Young Eun" uniqKey="Ha Y" first="Young Eun" last="Ha">Young Eun Ha</name><affiliation wicri:level="1"><nlm:aff id="aff1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Kang, Cheol In" sort="Kang, Cheol In" uniqKey="Kang C" first="Cheol-In" last="Kang">Cheol-In Kang</name><affiliation wicri:level="1"><nlm:aff id="aff1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Kang, Ji Man" sort="Kang, Ji Man" uniqKey="Kang J" first="Ji-Man" last="Kang">Ji-Man Kang</name><affiliation wicri:level="3"><nlm:aff id="aff2">Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Kim, Yae Jean" sort="Kim, Yae Jean" uniqKey="Kim Y" first="Yae-Jean" last="Kim">Yae-Jean Kim</name><affiliation wicri:level="3"><nlm:aff id="aff2">Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Huh, Hee Jae" sort="Huh, Hee Jae" uniqKey="Huh H" first="Hee Jae" last="Huh">Hee Jae Huh</name><affiliation wicri:level="3"><nlm:aff id="aff3">Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Ki, Chang Seok" sort="Ki, Chang Seok" uniqKey="Ki C" first="Chang-Seok" last="Ki">Chang-Seok Ki</name><affiliation wicri:level="3"><nlm:aff id="aff3">Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Jeong, Byeong Ho" sort="Jeong, Byeong Ho" uniqKey="Jeong B" first="Byeong-Ho" last="Jeong">Byeong-Ho Jeong</name><affiliation wicri:level="3"><nlm:aff id="aff4">Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Park, Jinkyeong" sort="Park, Jinkyeong" uniqKey="Park J" first="Jinkyeong" last="Park">Jinkyeong Park</name><affiliation wicri:level="3"><nlm:aff id="aff5">Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Chung, Chi Ryang" sort="Chung, Chi Ryang" uniqKey="Chung C" first="Chi Ryang" last="Chung">Chi Ryang Chung</name><affiliation wicri:level="3"><nlm:aff id="aff5">Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Chung, Doo Ryeon" sort="Chung, Doo Ryeon" uniqKey="Chung D" first="Doo Ryeon" last="Chung">Doo Ryeon Chung</name><affiliation wicri:level="1"><nlm:aff id="aff1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Song, Jae Hoon" sort="Song, Jae Hoon" uniqKey="Song J" first="Jae-Hoon" last="Song">Jae-Hoon Song</name><affiliation wicri:level="1"><nlm:aff id="aff1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Peck, Kyong Ran" sort="Peck, Kyong Ran" uniqKey="Peck K" first="Kyong Ran" last="Peck">Kyong Ran Peck</name><affiliation wicri:level="1"><nlm:aff id="aff1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27519621</idno><idno type="pmc">7112644</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112644</idno><idno type="RBID">PMC:7112644</idno><idno type="doi">10.1016/j.jinf.2016.08.005</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">000E65</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000E65</idno><idno type="wicri:Area/Pmc/Curation">000E65</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000E65</idno><idno type="wicri:Area/Pmc/Checkpoint">000A36</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000A36</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:27519621</idno><idno type="wicri:Area/PubMed/Corpus">001005</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001005</idno><idno type="wicri:Area/PubMed/Curation">001005</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001005</idno><idno type="wicri:Area/PubMed/Checkpoint">000F40</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000F40</idno><idno type="wicri:Area/Ncbi/Merge">001743</idno><idno type="wicri:Area/Ncbi/Curation">001743</idno><idno type="wicri:Area/Ncbi/Checkpoint">001743</idno><idno type="wicri:doubleKey">0163-4453:2016:Ko J:predictive:factors:for</idno><idno type="wicri:Area/Main/Merge">001069</idno><idno type="wicri:Area/Main/Curation">001065</idno><idno type="wicri:Area/Main/Exploration">001065</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Predictive factors for pneumonia development and progression to respiratory failure in MERS-CoV infected patients</title><author><name sortKey="Ko, Jae Hoon" sort="Ko, Jae Hoon" uniqKey="Ko J" first="Jae-Hoon" last="Ko">Jae-Hoon Ko</name><affiliation wicri:level="1"><nlm:aff id="aff1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Park, Ga Eun" sort="Park, Ga Eun" uniqKey="Park G" first="Ga Eun" last="Park">Ga Eun Park</name><affiliation wicri:level="1"><nlm:aff id="aff1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Lee, Ji Yeon" sort="Lee, Ji Yeon" uniqKey="Lee J" first="Ji Yeon" last="Lee">Ji Yeon Lee</name><affiliation wicri:level="1"><nlm:aff id="aff1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Lee, Ji Yong" sort="Lee, Ji Yong" uniqKey="Lee J" first="Ji Yong" last="Lee">Ji Yong Lee</name><affiliation wicri:level="1"><nlm:aff id="aff1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Cho, Sun Young" sort="Cho, Sun Young" uniqKey="Cho S" first="Sun Young" last="Cho">Sun Young Cho</name><affiliation wicri:level="1"><nlm:aff id="aff1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Ha, Young Eun" sort="Ha, Young Eun" uniqKey="Ha Y" first="Young Eun" last="Ha">Young Eun Ha</name><affiliation wicri:level="1"><nlm:aff id="aff1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Kang, Cheol In" sort="Kang, Cheol In" uniqKey="Kang C" first="Cheol-In" last="Kang">Cheol-In Kang</name><affiliation wicri:level="1"><nlm:aff id="aff1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Kang, Ji Man" sort="Kang, Ji Man" uniqKey="Kang J" first="Ji-Man" last="Kang">Ji-Man Kang</name><affiliation wicri:level="3"><nlm:aff id="aff2">Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Kim, Yae Jean" sort="Kim, Yae Jean" uniqKey="Kim Y" first="Yae-Jean" last="Kim">Yae-Jean Kim</name><affiliation wicri:level="3"><nlm:aff id="aff2">Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Huh, Hee Jae" sort="Huh, Hee Jae" uniqKey="Huh H" first="Hee Jae" last="Huh">Hee Jae Huh</name><affiliation wicri:level="3"><nlm:aff id="aff3">Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Ki, Chang Seok" sort="Ki, Chang Seok" uniqKey="Ki C" first="Chang-Seok" last="Ki">Chang-Seok Ki</name><affiliation wicri:level="3"><nlm:aff id="aff3">Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Jeong, Byeong Ho" sort="Jeong, Byeong Ho" uniqKey="Jeong B" first="Byeong-Ho" last="Jeong">Byeong-Ho Jeong</name><affiliation wicri:level="3"><nlm:aff id="aff4">Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Park, Jinkyeong" sort="Park, Jinkyeong" uniqKey="Park J" first="Jinkyeong" last="Park">Jinkyeong Park</name><affiliation wicri:level="3"><nlm:aff id="aff5">Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Chung, Chi Ryang" sort="Chung, Chi Ryang" uniqKey="Chung C" first="Chi Ryang" last="Chung">Chi Ryang Chung</name><affiliation wicri:level="3"><nlm:aff id="aff5">Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Chung, Doo Ryeon" sort="Chung, Doo Ryeon" uniqKey="Chung D" first="Doo Ryeon" last="Chung">Doo Ryeon Chung</name><affiliation wicri:level="1"><nlm:aff id="aff1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Song, Jae Hoon" sort="Song, Jae Hoon" uniqKey="Song J" first="Jae-Hoon" last="Song">Jae-Hoon Song</name><affiliation wicri:level="1"><nlm:aff id="aff1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Peck, Kyong Ran" sort="Peck, Kyong Ran" uniqKey="Peck K" first="Kyong Ran" last="Peck">Kyong Ran Peck</name><affiliation wicri:level="1"><nlm:aff id="aff1">Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author></analytic><series><title level="j">The Journal of Infection</title><idno type="ISSN">0163-4453</idno><idno type="eISSN">1532-2742</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Comorbidity</term><term>Coronavirus Infections (epidemiology)</term><term>Coronavirus Infections (physiopathology)</term><term>Disease Outbreaks</term><term>Disease Progression</term><term>Electronic Health Records</term><term>Female</term><term>Hospitals, University</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Pneumonia (epidemiology)</term><term>Pneumonia (physiopathology)</term><term>Republic of Korea (epidemiology)</term><term>Respiratory Insufficiency (epidemiology)</term><term>Risk Factors</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Comorbidité</term><term>Dossiers médicaux électroniques</term><term>Facteurs de risque</term><term>Femelle</term><term>Flambées de maladies</term><term>Humains</term><term>Hôpitaux universitaires</term><term>Infections à coronavirus (physiopathologie)</term><term>Infections à coronavirus (épidémiologie)</term><term>Insuffisance respiratoire (épidémiologie)</term><term>Mâle</term><term>Pneumopathie infectieuse (physiopathologie)</term><term>Pneumopathie infectieuse (épidémiologie)</term><term>République de Corée (épidémiologie)</term><term>Sujet âgé</term><term>Évolution de la maladie</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia</term><term>Republic of Korea</term><term>Respiratory Insufficiency</term></keywords><keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie infectieuse</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections à coronavirus</term><term>Insuffisance respiratoire</term><term>Pneumopathie infectieuse</term><term>République de Corée</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Comorbidity</term><term>Disease Outbreaks</term><term>Disease Progression</term><term>Electronic Health Records</term><term>Female</term><term>Hospitals, University</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Risk Factors</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Comorbidité</term><term>Dossiers médicaux électroniques</term><term>Facteurs de risque</term><term>Femelle</term><term>Flambées de maladies</term><term>Humains</term><term>Hôpitaux universitaires</term><term>Mâle</term><term>Sujet âgé</term><term>Évolution de la maladie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Summary</title><sec><title>Background</title><p>After the 2015 Middle East respiratory syndrome (MERS) outbreak in Korea, prediction of pneumonia development and progression to respiratory failure was emphasized in control of MERS outbreak.</p></sec><sec><title>Methods</title><p>MERS-CoV infected patients who were managed in a tertiary care center during the 2015 Korean MERS outbreak were reviewed. To analyze predictive factors for pneumonia development and progression to respiratory failure, we evaluated clinical variables measured within three days from symptom onset.</p></sec><sec><title>Results</title><p>A total of 45 patients were included in the study: 13 patients (28.9%) did not develop pneumonia, 19 developed pneumonia without respiratory failure (42.2%), and 13 progressed to respiratory failures (28.9%). The identified predictive factors for pneumonia development included age ≥45 years, fever ≥37.5 °C, thrombocytopenia, lymphopenia, CRP ≥ 2 mg/dL, and a threshold cycle value of PCR less than 28.5. For respiratory failure, the indicators included male, hypertension, low albumin concentration, thrombocytopenia, lymphopenia, and CRP ≥ 4 mg/dL (all <italic>P</italic> < 0.05). With ≥ two predictive factors for pneumonia development, 100% of patients developed pneumonia. Patients lacking the predictive factors did not progress to respiratory failure.</p></sec><sec><title>Conclusion</title><p>For successful control of MERS outbreak, MERS-CoV infected patients with ≥ two predictive factors should be intensively managed from the initial presentation.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Zumla, A" uniqKey="Zumla A">A. Zumla</name></author><author><name sortKey="Hui, D S" uniqKey="Hui D">D.S. Hui</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S. Perlman</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Kim, Y" uniqKey="Kim Y">Y. Kim</name></author><author><name sortKey="Lee, S" uniqKey="Lee S">S. Lee</name></author><author><name sortKey="Chu, C" uniqKey="Chu C">C. Chu</name></author><author><name sortKey="Choe, S" uniqKey="Choe S">S. Choe</name></author><author><name sortKey="Hong, S" uniqKey="Hong S">S. Hong</name></author><author><name sortKey="Shin, Y" uniqKey="Shin Y">Y. Shin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cowling, B J" uniqKey="Cowling B">B.J. Cowling</name></author><author><name sortKey="Park, M" uniqKey="Park M">M. Park</name></author><author><name sortKey="Fang, V J" uniqKey="Fang V">V.J. Fang</name></author><author><name sortKey="Wu, P" uniqKey="Wu P">P. Wu</name></author><author><name sortKey="Leung, G M" uniqKey="Leung G">G.M. Leung</name></author><author><name sortKey="Wu, J T" uniqKey="Wu J">J.T. Wu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nishiura, H" uniqKey="Nishiura H">H. Nishiura</name></author><author><name sortKey="Endo, A" uniqKey="Endo A">A. Endo</name></author><author><name sortKey="Saitoh, M" uniqKey="Saitoh M">M. Saitoh</name></author><author><name sortKey="Kinoshita, R" uniqKey="Kinoshita R">R. Kinoshita</name></author><author><name sortKey="Ueno, R" uniqKey="Ueno R">R. Ueno</name></author><author><name sortKey="Nakaoka, S" uniqKey="Nakaoka S">S. Nakaoka</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chowell, G" uniqKey="Chowell G">G. Chowell</name></author><author><name sortKey="Abdirizak, F" uniqKey="Abdirizak F">F. Abdirizak</name></author><author><name sortKey="Lee, S" uniqKey="Lee S">S. Lee</name></author><author><name sortKey="Lee, J" uniqKey="Lee J">J. Lee</name></author><author><name sortKey="Jung, E" uniqKey="Jung E">E. Jung</name></author><author><name sortKey="Nishiura, H" uniqKey="Nishiura H">H. Nishiura</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Park, G E" uniqKey="Park G">G.E. Park</name></author><author><name sortKey="Ko, J H" uniqKey="Ko J">J.H. Ko</name></author><author><name sortKey="Peck, K R" uniqKey="Peck K">K.R. Peck</name></author><author><name sortKey="Lee, J Y" uniqKey="Lee J">J.Y. Lee</name></author><author><name sortKey="Lee, J Y" uniqKey="Lee J">J.Y. Lee</name></author><author><name sortKey="Cho, S Y" uniqKey="Cho S">S.Y. Cho</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cho, S Y" uniqKey="Cho S">S.Y. Cho</name></author><author><name sortKey="Kang, J M" uniqKey="Kang J">J.M. Kang</name></author><author><name sortKey="Ha, Y E" uniqKey="Ha Y">Y.E. Ha</name></author><author><name sortKey="Park, G E" uniqKey="Park G">G.E. Park</name></author><author><name sortKey="Lee, J Y" uniqKey="Lee J">J.Y. Lee</name></author><author><name sortKey="Ko, J H" uniqKey="Ko J">J.H. Ko</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mizumoto, K" uniqKey="Mizumoto K">K. Mizumoto</name></author><author><name sortKey="Endo, A" uniqKey="Endo A">A. Endo</name></author><author><name sortKey="Chowell, G" uniqKey="Chowell G">G. Chowell</name></author><author><name sortKey="Miyamatsu, Y" uniqKey="Miyamatsu Y">Y. Miyamatsu</name></author><author><name sortKey="Saitoh, M" uniqKey="Saitoh M">M. Saitoh</name></author><author><name sortKey="Nishiura, H" uniqKey="Nishiura H">H. Nishiura</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Corman, V M" uniqKey="Corman V">V.M. Corman</name></author><author><name sortKey="Albarrak, A M" uniqKey="Albarrak A">A.M. Albarrak</name></author><author><name sortKey="Omrani, A S" uniqKey="Omrani A">A.S. Omrani</name></author><author><name sortKey="Albarrak, M M" uniqKey="Albarrak M">M.M. Albarrak</name></author><author><name sortKey="Farah, M E" uniqKey="Farah M">M.E. Farah</name></author><author><name sortKey="Almasri, M" uniqKey="Almasri M">M. Almasri</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Feikin, D R" uniqKey="Feikin D">D.R. Feikin</name></author><author><name sortKey="Alraddadi, B" uniqKey="Alraddadi B">B. Alraddadi</name></author><author><name sortKey="Qutub, M" uniqKey="Qutub M">M. Qutub</name></author><author><name sortKey="Shabouni, O" uniqKey="Shabouni O">O. Shabouni</name></author><author><name sortKey="Curns, A" uniqKey="Curns A">A. Curns</name></author><author><name sortKey="Oboho, I K" uniqKey="Oboho I">I.K. Oboho</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Majumder, M S" uniqKey="Majumder M">M.S. Majumder</name></author><author><name sortKey="Kluberg, S A" uniqKey="Kluberg S">S.A. Kluberg</name></author><author><name sortKey="Mekaru, S R" uniqKey="Mekaru S">S.R. Mekaru</name></author><author><name sortKey="Brownstein, J S" uniqKey="Brownstein J">J.S. Brownstein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Saad, M" uniqKey="Saad M">M. Saad</name></author><author><name sortKey="Omrani, A S" uniqKey="Omrani A">A.S. Omrani</name></author><author><name sortKey="Baig, K" uniqKey="Baig K">K. Baig</name></author><author><name sortKey="Bahloul, A" uniqKey="Bahloul A">A. Bahloul</name></author><author><name sortKey="Elzein, F" uniqKey="Elzein F">F. Elzein</name></author><author><name sortKey="Matin, M A" uniqKey="Matin M">M.A. Matin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Banik, G R" uniqKey="Banik G">G.R. Banik</name></author><author><name sortKey="Alqahtani, A S" uniqKey="Alqahtani A">A.S. Alqahtani</name></author><author><name sortKey="Booy, R" uniqKey="Booy R">R. Booy</name></author><author><name sortKey="Rashid, H" uniqKey="Rashid H">H. Rashid</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Madani, T A" uniqKey="Madani T">T.A. Madani</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Oboho, I K" uniqKey="Oboho I">I.K. Oboho</name></author><author><name sortKey="Tomczyk, S M" uniqKey="Tomczyk S">S.M. Tomczyk</name></author><author><name sortKey="Al Asmari, A M" uniqKey="Al Asmari A">A.M. Al-Asmari</name></author><author><name sortKey="Banjar, A A" uniqKey="Banjar A">A.A. Banjar</name></author><author><name sortKey="Al Mugti, H" uniqKey="Al Mugti H">H. Al-Mugti</name></author><author><name sortKey="Aloraini, M S" uniqKey="Aloraini M">M.S. Aloraini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Woolf, B" uniqKey="Woolf B">B. Woolf</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Al Ghamdi, M" uniqKey="Al Ghamdi M">M. Al Ghamdi</name></author><author><name sortKey="Alghamdi, K M" uniqKey="Alghamdi K">K.M. Alghamdi</name></author><author><name sortKey="Ghandoora, Y" uniqKey="Ghandoora Y">Y. Ghandoora</name></author><author><name sortKey="Alzahrani, A" uniqKey="Alzahrani A">A. Alzahrani</name></author><author><name sortKey="Salah, F" uniqKey="Salah F">F. Salah</name></author><author><name sortKey="Alsulami, A" uniqKey="Alsulami A">A. Alsulami</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Modjarrad, K" uniqKey="Modjarrad K">K. Modjarrad</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chan, J F" uniqKey="Chan J">J.F. Chan</name></author><author><name sortKey="Yao, Y" uniqKey="Yao Y">Y. Yao</name></author><author><name sortKey="Yeung, M L" uniqKey="Yeung M">M.L. Yeung</name></author><author><name sortKey="Deng, W" uniqKey="Deng W">W. Deng</name></author><author><name sortKey="Bao, L" uniqKey="Bao L">L. Bao</name></author><author><name sortKey="Jia, L" uniqKey="Jia L">L. Jia</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Min, C K" uniqKey="Min C">C.K. Min</name></author><author><name sortKey="Cheon, S" uniqKey="Cheon S">S. Cheon</name></author><author><name sortKey="Ha, N Y" uniqKey="Ha N">N.Y. Ha</name></author><author><name sortKey="Sohn, K M" uniqKey="Sohn K">K.M. Sohn</name></author><author><name sortKey="Kim, Y" uniqKey="Kim Y">Y. Kim</name></author><author><name sortKey="Aigerim, A" uniqKey="Aigerim A">A. Aigerim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Arabi, Y M" uniqKey="Arabi Y">Y.M. Arabi</name></author><author><name sortKey="Arifi, A A" uniqKey="Arifi A">A.A. Arifi</name></author><author><name sortKey="Balkhy, H H" uniqKey="Balkhy H">H.H. Balkhy</name></author><author><name sortKey="Najm, H" uniqKey="Najm H">H. Najm</name></author><author><name sortKey="Aldawood, A S" uniqKey="Aldawood A">A.S. Aldawood</name></author><author><name sortKey="Ghabashi, A" uniqKey="Ghabashi A">A. Ghabashi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guery, B" uniqKey="Guery B">B. Guery</name></author><author><name sortKey="Poissy, J" uniqKey="Poissy J">J. Poissy</name></author><author><name sortKey="El Mansouf, L" uniqKey="El Mansouf L">L. el Mansouf</name></author><author><name sortKey="Sejourne, C" uniqKey="Sejourne C">C. Sejourne</name></author><author><name sortKey="Ettahar, N" uniqKey="Ettahar N">N. Ettahar</name></author><author><name sortKey="Lemaire, X" uniqKey="Lemaire X">X. Lemaire</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Choi, K W" uniqKey="Choi K">K.W. Choi</name></author><author><name sortKey="Chau, T N" uniqKey="Chau T">T.N. Chau</name></author><author><name sortKey="Tsang, O" uniqKey="Tsang O">O. Tsang</name></author><author><name sortKey="Tso, E" uniqKey="Tso E">E. Tso</name></author><author><name sortKey="Chiu, M C" uniqKey="Chiu M">M.C. Chiu</name></author><author><name sortKey="Tong, W L" uniqKey="Tong W">W.L. Tong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lupovitch, A" uniqKey="Lupovitch A">A. Lupovitch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, M" uniqKey="Yang M">M. Yang</name></author><author><name sortKey="Ng, M H" uniqKey="Ng M">M.H. Ng</name></author><author><name sortKey="Li, C K" uniqKey="Li C">C.K. Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Le, V B" uniqKey="Le V">V.B. Le</name></author><author><name sortKey="Schneider, J G" uniqKey="Schneider J">J.G. Schneider</name></author><author><name sortKey="Boergeling, Y" uniqKey="Boergeling Y">Y. Boergeling</name></author><author><name sortKey="Berri, F" uniqKey="Berri F">F. Berri</name></author><author><name sortKey="Ducatez, M" uniqKey="Ducatez M">M. Ducatez</name></author><author><name sortKey="Guerin, J L" uniqKey="Guerin J">J.L. Guerin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ying, T" uniqKey="Ying T">T. Ying</name></author><author><name sortKey="Li, W" uniqKey="Li W">W. Li</name></author><author><name sortKey="Dimitrov, D S" uniqKey="Dimitrov D">D.S. Dimitrov</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chu, H" uniqKey="Chu H">H. Chu</name></author><author><name sortKey="Zhou, J" uniqKey="Zhou J">J. Zhou</name></author><author><name sortKey="Wong, B H" uniqKey="Wong B">B.H. Wong</name></author><author><name sortKey="Li, C" uniqKey="Li C">C. Li</name></author><author><name sortKey="Chan, J F" uniqKey="Chan J">J.F. Chan</name></author><author><name sortKey="Cheng, Z S" uniqKey="Cheng Z">Z.S. Cheng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Assiri, A" uniqKey="Assiri A">A. Assiri</name></author><author><name sortKey="Al Tawfiq, J A" uniqKey="Al Tawfiq J">J.A. Al-Tawfiq</name></author><author><name sortKey="Al Rabeeah, A A" uniqKey="Al Rabeeah A">A.A. Al-Rabeeah</name></author><author><name sortKey="Al Rabiah, F A" uniqKey="Al Rabiah F">F.A. Al-Rabiah</name></author><author><name sortKey="Al Hajjar, S" uniqKey="Al Hajjar S">S. Al-Hajjar</name></author><author><name sortKey="Al Barrak, A" uniqKey="Al Barrak A">A. Al-Barrak</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chan, J F" uniqKey="Chan J">J.F. Chan</name></author><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="To, K K" uniqKey="To K">K.K. To</name></author><author><name sortKey="Cheng, V C" uniqKey="Cheng V">V.C. Cheng</name></author><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Corée du Sud</li></country><region><li>Région capitale de Séoul</li></region><settlement><li>Séoul</li></settlement></list><tree><country name="Corée du Sud"><region name="Région capitale de Séoul"><name sortKey="Ko, Jae Hoon" sort="Ko, Jae Hoon" uniqKey="Ko J" first="Jae-Hoon" last="Ko">Jae-Hoon Ko</name></region><name sortKey="Cho, Sun Young" sort="Cho, Sun Young" uniqKey="Cho S" first="Sun Young" last="Cho">Sun Young Cho</name><name sortKey="Chung, Chi Ryang" sort="Chung, Chi Ryang" uniqKey="Chung C" first="Chi Ryang" last="Chung">Chi Ryang Chung</name><name sortKey="Chung, Doo Ryeon" sort="Chung, Doo Ryeon" uniqKey="Chung D" first="Doo Ryeon" last="Chung">Doo Ryeon Chung</name><name sortKey="Ha, Young Eun" sort="Ha, Young Eun" uniqKey="Ha Y" first="Young Eun" last="Ha">Young Eun Ha</name><name sortKey="Huh, Hee Jae" sort="Huh, Hee Jae" uniqKey="Huh H" first="Hee Jae" last="Huh">Hee Jae Huh</name><name sortKey="Jeong, Byeong Ho" sort="Jeong, Byeong Ho" uniqKey="Jeong B" first="Byeong-Ho" last="Jeong">Byeong-Ho Jeong</name><name sortKey="Kang, Cheol In" sort="Kang, Cheol In" uniqKey="Kang C" first="Cheol-In" last="Kang">Cheol-In Kang</name><name sortKey="Kang, Ji Man" sort="Kang, Ji Man" uniqKey="Kang J" first="Ji-Man" last="Kang">Ji-Man Kang</name><name sortKey="Ki, Chang Seok" sort="Ki, Chang Seok" uniqKey="Ki C" first="Chang-Seok" last="Ki">Chang-Seok Ki</name><name sortKey="Kim, Yae Jean" sort="Kim, Yae Jean" uniqKey="Kim Y" first="Yae-Jean" last="Kim">Yae-Jean Kim</name><name sortKey="Lee, Ji Yeon" sort="Lee, Ji Yeon" uniqKey="Lee J" first="Ji Yeon" last="Lee">Ji Yeon Lee</name><name sortKey="Lee, Ji Yong" sort="Lee, Ji Yong" uniqKey="Lee J" first="Ji Yong" last="Lee">Ji Yong Lee</name><name sortKey="Park, Ga Eun" sort="Park, Ga Eun" uniqKey="Park G" first="Ga Eun" last="Park">Ga Eun Park</name><name sortKey="Park, Jinkyeong" sort="Park, Jinkyeong" uniqKey="Park J" first="Jinkyeong" last="Park">Jinkyeong Park</name><name sortKey="Peck, Kyong Ran" sort="Peck, Kyong Ran" uniqKey="Peck K" first="Kyong Ran" last="Peck">Kyong Ran Peck</name><name sortKey="Song, Jae Hoon" sort="Song, Jae Hoon" uniqKey="Song J" first="Jae-Hoon" last="Song">Jae-Hoon Song</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001065 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001065 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= MersV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:7112644
|texte= Predictive factors for pneumonia development and progression to respiratory failure in MERS-CoV infected patients
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:27519621" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a MersV1
| This area was generated with Dilib version V0.6.33. |  |